The most striking feature of this form of vasculitis is a purplish rash, typically on the lower legs and buttocks. The objective of this study was to determine the factors associated with the development. In the presence of certain clinical features the possibility of an underlying vasculitic disease must be considered. The source of information was medical records and a data gathering guide containing the studied variables was used. There are many different conditions that feature vasculitis. Among the 12 patients with recurrent or chronic henochschonlein purpura, three had arthritis, four exhibited signs and symptoms of abdominal involvement and seven of kidney disease. Henochschonlein purpura, henoch schonlein purpura, henochschoenlein purpura, henoch schoenlein purpura, hsp, iga vasculitis. Henochschonlein purpura is a small vessel vasculitis that affects mainly pediatric patients, characterized by the tetrad of palpable purpura, abdominal pain, arthralgia or arthritis and kidney injury. The disease is characterized by abnormal deposits of immunoglobulin a an antibody in the blood vessels, leading to their inflammation vasculitis. Henoch schonlein purpura also known as anaphylactoid purpura is a type of vasculitis that affects small blood vessels and characterized by elevated immunoglobulin a iga. However, all four elements of this tetrad are not required for diagnosis. Henochschonlein purpura is a systemic vasculitis mediated by ig a, clinically.
Each of the forms of vasculitis tends to involve certain. Henoch schonlein purpura, henoch schonlein purpura, henoch schoenlein purpura, henoch schoenlein purpura, hsp, iga vasculitis, immunoglobulin a vasculitis. Hsp is usually selflimiting in 94% of children and 89% of adults. Henochschonlein purpura hsp is the most common form of pediatric vasculitis. A retrospective descriptive study of patients with scholein henoch purpura diagnosis was conducted for 4 years. Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of hsp. When blood vessels get inflamed, they can bleed into the skin, causing a reddishpurple rash purpura. Henoch schonlein purpura is an inflammation of the small blood vessels of the skin, joints, bowels and kidneys. Longterm prognosis is mainly conditioned by renal involvement, which can appear at onset or during the course of the disease. Please use one of the following formats to cite this article in your essay, paper or report. Diatesis hemorragica, reaccion a farmacos, sepsis, malos tratos. The objective of this study was to determine the factors associated with the development and course of this disease. Schonleinhenoch purpura is a systemic vasculitis due to igamediated hypersensitivity, almost exclusively affecting the pediatric age group.
Dec 10, 2018 henoch schonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels. Purpura, arthritis, and abdominal pain are known as the classic triad of henochschonlein purpura. Henoch schonlein purpura presenting as hemorrhagic vesicles and bullae. Hsp presents with purple spots on the skin purpura, arthralgia, digestive problems, and kidney injury.
Schonleinhenoch purpura is the most common infantile vasculitis and is mostly clinically diagnosed. Purpura occur in all cases, joint pains and arthritis in 80%, and abdominal pain in 62%. Background 1st described in 1801 by william heberden, a physician in london, who wrote about a. Schonlein henoch purpura is the most common infantile vasculitis and is mostly clinically diagnosed.
Henochschonlein purpura hsp is an immunemediated vasculitis. It affects children, mainly males, in 90% of cases the four main clinical features include purpura rash, abdominal pain, arthralgia and renal involvement. Henoch schonlein purpura associated with malignancy in adults. Henochschonlein purpura, who presented to our department with cutaneous manifestations. Henochschonlein purpura definition of henochschonlein. Health professionals diagnosis henoch schonlein purpura through blood tests elevated iga. A retrospective descriptive study of patients with scholeinhenoch purpura diagnosis was conducted for. Longterm outcome and treatment academic dissertation to be presented with the assent of the faculty of medicine, university of oulu, for public. Serum c5b 9 terminal complement complex level, a sensitive indicator of disease activity in patients with henoch schonlein purpura. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed.
She has torpid evolution, and gastrointestinal and renal complications. Symptoms of this disease include skin lesions, joint pain, blood in urine hematuria, and abdominal pain. Henochschonlein purpura hsp, also called immunoglobulin a vasculitis. Mar 14, 2019 henochschonlein purpura hsp is an acute immunoglobulin a igamediated disorder characterized by a generalized vasculitis involving the small vessels of the skin, the gastrointestinal gi tract, the kidneys, the joints, and, rarely, the lungs and the central nervous system cns. Serum c5b 9 terminal complement complex level, a sensitive indicator of disease activity in patients with henochschonlein purpura. Henoch schonlein purpura is a particular form of blood vessel inflammation called vasculitis henoch schonlein purpura frequently follows an infection of the throat or breathing passages, but it can be induced by certain medications. Henochschonlein purpura also known as anaphylactoid purpura is a type of vasculitis that affects small blood vessels and characterized by elevated immunoglobulin a iga. The palpable purpura is the most important sing and constitute the basis of clinical sine qua non to suspect or establish the diagnosis.
Henochschonlein purpura symptoms and causes mayo clinic. The prognosis of hsp in this study is still uncertain, since we do not have enough record to determine so. Henochschonlein purpura hsp is an immune mechanism leukocytoclastic vasculitis with small vessel involvement. Hsp is most common in younger pts clinical red maculopapules on legs and buttocks. Henochschonlein purpura anaphylactoid purpura, vascular purpura internal medicine an acquired form of small vessel vasculitis with igadominant immune deposits affecting small vesselsarteries, capillaries, venules, typically of the skin, gut, and glomeruli, associated with arthralgia andor arthritis. Thrombocytopenic purpura is mostly responsible for episodes of mucocutaneous bleeding. Precedidas por una infecciondel tracto respiratorio superiorpatologia mediada por elsistema inmuneinducida por factoresambientales. Henochschonlein purpura is a small vessel vasculitis that affects mainly pediatric patients, characterized by the tetrad of palpable purpura, abdominal pain, arthralgia or arthritis. Background 1st described in 1801 by william heberden, a physician in london, who wrote about a case of a 5 year old boy with hematuria, abdominal pain, joint pains and skin rash.
The prognosis of hsp in this study is still uncertain, since we do. Some include gastrointestinal hemorrhage as a fourth criterion. This page includes the following topics and synonyms. Henoch schonlein purpura hsp is an immunemediated vasculitis.
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